There were a few relations:
- John Adams, the second president, was the father of John Quincy Adams, the sixth president.
- George Herbert Walker Bush, the forty-first president, was the father of George Walker Bush, the forty-third.
- William Henry Harrison, the ninth president, was the grandfather of Benjamin Harrison, the twenty-third president.
- James Madison, the fourth president, and Zachary Taylor, the twelfth, were second cousins.